Researchers Develop Universal Flu Vaccine with Nanoparticles That Protects Against Six Different Influenza Viruses in Mice
January 6, 2020
A novel nanoparticle vaccine that combines two major influenza proteins is effective in providing broad, long-lasting protection against influenza virus in mice, showing promise as a universal flu vaccine, according to a study by the Institute for Biomedical Sciences at Georgia State University.
Targeted immunization against bacterial flagellin, a protein that forms the appendage that enables bacterial mobility, can beneficially alter the intestinal microbiota, decreasing the bacteria’s ability to cause inflammation and thus protecting against an array of chronic inflammatory diseases, according to a new study by the Institute for Biomedical Sciences and the Neuroscience Institute at Georgia State University.
A new antiviral drug that induces mutations in the genetic material of influenza virus is highly effective in treating influenza infection in animals and human airway tissue and could be a groundbreaking advance in influenza therapy, according to a study by the Institute for Biomedical Sciences at Georgia State University.
The presence of specific microbiota, or microorganisms that live in the digestive tract, can prevent and cure rotavirus infection, which is the leading cause of severe, life-threatening diarrhea in children worldwide, according to a new study by the Institute for Biomedical Sciences at Georgia State University.
Creating mutations in a key Ebola virus protein that helps the deadly virus escape from the body’s defenses can make the virus unable to produce sickness and activate protective immunity in the infected host, according to a study by the Institute for Biomedical Sciences at Georgia State University.
Targeting specific areas of the measles virus polymerase, a protein complex that copies the viral genome, can effectively fight the measles virus and be used as an approach to developing new antiviral drugs to treat the serious infectious disease, according to a study by the Institute for Biomedical Sciences at Georgia State University published in PLoS Pathogens.
Blocking the ability of the bacterial pathogen that causes gonorrhea to uptake the mineral zinc can stop infection by this widespread sexually transmitted infection, according to a study by the Institute for Biomedical Sciences at Georgia State University.
A new review book is designed to make studying easier for students in medical school, graduate microbiology programs or undergraduate pre-med programs and individuals preparing for the United States Medical Licensing Examination (USMLE).
Influenza remains a major public health risk, and Dr. Baozhong Wang, associate professor in Georgia State University’s Institute for Biomedical Sciences, has received a five-year, $3.26 million federal grant to combat this threat by developing a universal vaccine that offers more protection against influenza than seasonal vaccines.
Small molecules found in fecal matter could provide clues to the early inflammation found in chronic gut conditions, such as inflammatory bowel disease (IBD), and serve as new biomarkers for diagnosis, according to a study led by the Institute for Biomedical Sciences at Georgia State University.
A unique adjuvant, a substance that enhances the body’s immune response to toxins and foreign matter, can prevent vaccine-enhanced respiratory disease, a sickness that has posed a major hurdle in vaccine development for respiratory syncytial virus (RSV), according to a study led by the Institute for Biomedical Sciences at Georgia State University.
Dr. Cynthia Nau Cornelissen, a leading researcher in the study of infectious diseases, including sexually transmitted infections (STIs), has been named director of the Center for Translational Immunology in the Institute for Biomedical Sciences at Georgia State University.
Your body is much more than just flesh and bones. It’s a complex ecosystem teeming with trillions of microorganisms, which — as Georgia State scientists are finding — may be the key to understanding and treating all kinds of disease.
With flu vaccines often unreliable and many antiviral drugs no longer effective, a Georgia State professor has developed a new way to fight the ever-evolving, omnipresent threat of the flu — by tricking it.
Exposure to microbiota, or microorganisms such as bacteria, in the early stages of life plays a crucial role in establishing optimal conditions in the intestine that inhibit the development of colon cancer in adulthood, according to a study led by Georgia State University.
Dr. Richard Plemper, a professor in Georgia State University’s Institute for Biomedical Sciences (IBMS), has received a five-year, $5 million federal grant to develop an antiviral drug to treat influenza virus infections.
Georgia State University is part of a national group of leading innovative institutions that has received a $2.4 million grant from the Strada Education Network to redesign the college-to-career pathway.
Dr. Baozhong Wang, associate professor in Georgia State University’s Institute for Biomedical Sciences, has received a five-year, $3.86 million federal grant to develop a universal flu vaccine using a microneedle patch that will protect against any strain of the influenza virus.
Dr. Jun Zou, a research assistant professor in the Institute for Biomedical Sciences at Georgia State University, has received a four-year, $552,000 grant to study how dietary fiber can protect against diabetes and other disorders associated with metabolic syndrome.
Food additives known as dietary emulsifiers, commonly found in processed foods to improve texture and extend shelf life, may adversely affect anxiety-related and social behaviors in mice, Georgia State researchers have found.
Skin vaccination using a microneedle patch that contains the inactivated respiratory syncytial virus (RSV) and a compound that stimulates immune responses to the virus has been found to enhance protection against this serious disease and reduce inflammation in the body after exposure to the virus, according to a study led by Georgia State University.
Several new connections have been discovered between the proteins of the Ebola virus and human host cells, a finding that provides insight on ways to prevent the deadly Ebola virus from reproducing and could lead to novel ways to fight these lethal viral infections, according to a study led by Georgia State University, the University of California, San Francisco, and the Gladstone Institutes.
Adding highly refined fiber to processed foods could have negative effects on human health, such as promoting liver cancer, according to a new study by researchers at Georgia State University and the University of Toledo.
Researchers have identified how a viral protein, which plays a major role in causing deadly Nipah and Hendra virus infections, targets a critical function in human cells to suppress immune responses and promote fatal disease.
Georgia State University is ranked the second most innovative university in the nation and second in the country for its commitment to undergraduate teaching in the 2019 Best Colleges edition of U.S. News & World Report magazine.
A gene from the deadly Ebola virus that allows the virus to escape from the human immune system has been identified in the genome of a group of bats that is found worldwide, including North America. The gene appears to have been stolen from the virus by the bats and adapted to regulate their own immune response, according to a recent study led by Georgia State University.
Advac, LLC, a vaccine research company founded by Sang-Moo Kang, a professor in the Institute for Biomedical Sciences at Georgia State University, has received $225,000 from the National Institutes of Health to develop a safer, more effective vaccine for human respiratory syncytial virus (RSV).
Dr. Christopher Basler, a professor in the Institute for Biomedical Sciences at Georgia State University, director of the university’s Center for Microbial Pathogenesis and a Georgia Research Alliance Eminent Scholar in Microbial Pathogenesis, has received a two-year, $419,100 federal grant to study a virus similar to Ebola virus that causes disease in animals but not in humans.
Inflammation is an important weapon in your immune system’s arsenal, but too much of it can hurt rather than heal. Across campus, Georgia State scientists are tackling the silent, simmering menace of chronic inflammation.
A new group of proteins called cytokines, critical for antimicrobial activity and repairing the damaged intestinal tissue found in inflammatory bowel disease (IBD), has been discovered by researchers in a study led by Georgia State University.
Georgia State University has received two four-year grants totaling nearly $6 million from the National Heart, Lung, and Blood Institute for research to identify a therapy that can counteract atherosclerosis, or the buildup of plaque in the arteries, and research to promote the regeneration of damaged vascular tissue after a heart attack or stroke.
Researchers have developed a universal vaccine to combat influenza A viruses that produces long-lasting immunity in mice and protects them against the limitations of seasonal flu vaccines, according to a study led by Georgia State University.
Consumption of dietary fiber can prevent obesity, metabolic syndrome and adverse changes in the intestine by promoting growth of “good” bacteria in the colon, according to a study led by Georgia State University.
Lactic acid bacteria, commonly used as probiotics to improve digestive health, can offer protection against different subtypes of influenza A virus, according to a study led by Georgia State University.
ATLANTA—Specific immune cells have the ability to produce a healing factor that can promote wound repair in the intestine, a finding that could lead to new, potential therapeutic treatments for inflammatory bowel disease (IBD), according to a new research study.
ATLANTA—Georgia State’s Institute for Biomedical Sciences (IBMS) has welcomed its first class of nine Ph.D. students enrolled in an innovative and interdisciplinary program meant to cultivate the next generation of leaders in the biomedical sector.
August 25, 2017
Associate Director of Communications Institute for Biomedical Sciences Georgia State University